- Cln Mutants
- cln1∆ cln2∆
- cln1∆ cln2∆ sic1∆
- cln1∆ cln2∆ cdh1∆
- cln1∆ cln2∆ bck2∆
- cln1∆ cln2∆ clb5∆ clb6∆
- cln1∆ cln2∆ cln3∆
- cln1∆ cln2∆ cln3∆ GAL-CLN2
- cln1∆ cln2∆ cln3∆ GAL-CLN3
- cln1∆ cln2∆ cln3∆ sic1∆
- cln1∆ cln2∆ cln3∆ cdh1∆
- cln1∆ cln2∆ cln3∆ multi-copy CLB5
- cln1∆ cln2∆ cln3∆ GAL-CLB5
- cln1∆ cln2∆ cln3∆ multicopy BCK2
- cln1∆ cln2∆ cln3∆ GAL-CLB2
- cln1∆ cln2∆ cln3∆ apc-ts
- GAL-SIC1 cln1∆ cln2∆
- GAL-SIC1 GAL-CLN2 cln1∆ cln2∆
- GAL-SIC1 cln1∆ cln2∆ cdh1∆
- GAL-SIC1 GAL-CLN2 cln1∆ cln2∆ cdh1∆
- GAL-CLN2 cln1∆ cln2∆ cdh1∆
- GAL-CLN2 cln1∆ cln2∆
- cdc14-ts GAL-CLN2
- cln3∆
- cln3∆ bck2∆
- cln3∆ bck2∆ GAL-CLN2 cln1∆ cln2∆
- cln3∆ bck2∆ multi-copy CLN2
- cln3∆ bck2∆ sic1∆
- GAL-CLN3
GAL-CLN2 cln1∆ cln2∆ cdh1∆
debug: ,
test user =
test db =
Simulation:
Change of parameters: ksn2'=0.12, ksn2"=0, kscdh=0, MDT=150, init CDH1T=CDH1=0.
Length of G1 phase: 153.7 min.
Mass at division: 0.61.
Experiments:
Cross, F.R., Archambault, V., Miller, M., Klovstad, M. (2002). Testing a mathematical model of the yeast cell cycle. Mol. Biol. Cell 13:52-70.
[Abstract] [Article]
[Abstract] [Article]
Experimental results: Fig. 3B, viable.
Comments: In our simulation, [BUD]max=0.5 <1, we suppose the morphogenesis
checkpoint
(Lew, 2000;
Ciliberto et al, 2003)
would cause a delay in mitosis.